For the record, I only invest via unit trusts, but I'm very picky who I buy into and I'm ruthless about cutting losses but never shy of taking a profit and moving the money elsewhere. I do not get it right every time, I have mistimed Gibbs at Jupiter Financial Opportunities recently and I have lost faith completely in Woodford at Invesco, but overall I'm doing OK. The time to sell equities is when you see all the articles telling you to "sell your granny and buy in to the market, the only way is up, it's different this time" etc... This approach works every time, though it still does make me nervous, I have to admit.